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Care365 medication guide
Spironolactone
Treats selected fluid, blood-pressure and aldosterone disorders. Hair-loss or acne use is off-label.
Drug information
Uses, directions and safety information for Spironolactone.
What it is used for
Treats selected fluid, blood-pressure and aldosterone disorders. Hair-loss or acne use is off-label.
How to use it
Use the prescribed dose with potassium and kidney-function monitoring appropriate to your situation.
Before use
Avoid high potassium, severe kidney impairment, Addison’s disease and contraindicated combinations.
Possible side effects
Nausea, cramps and breast or menstrual changes.
When to get medical help
Weakness, palpitations, fainting or severe rash needs assessment.
Medicines and interactions
Potassium supplements, ACE inhibitors/ARBs, NSAIDs and lithium require review.
Pregnancy and breastfeeding
The Canadian reference restricts pregnancy and breastfeeding; discuss alternatives.
Missed doses, storage and accidental exposure
Follow your own product’s missed-dose instructions. If you are unsure, ask a pharmacist before taking an extra dose. Contraceptives, injections and modified-release medicines may need a specific plan.
Keep the original packaging and follow its storage, expiry and disposal instructions. Keep medicines away from children and pets. Ask about refrigeration, after-opening limits and safe sharps disposal when relevant.
For suspected overdose or accidental swallowing, contact poison control or urgent medical care promptly. Call emergency services for breathing difficulty, collapse or a seizure.
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A healthcare professional assesses which care or referral is appropriate.
Plan your follow-up
Follow the advice you receive about treatment, monitoring and next steps.
Related condition guides
Learn about concerns where this medication may be discussed. Treatment depends on your individual assessment.
Prescription renewal and medication review
For a review of Spironolactone, have your current dose, reason for treatment, remaining supply, benefits, side effects and pharmacy details ready. Ask your pharmacist or prescriber whether a renewal assessment is available and appropriate. A prescription or renewal is not guaranteed.
Questions about Spironolactone
What is Spironolactone used for?
Treats selected fluid, blood-pressure and aldosterone disorders. Hair-loss or acne use is off-label.
How should I use Spironolactone?
Use the prescribed dose with potassium and kidney-function monitoring appropriate to your situation.
What side effects can Spironolactone cause?
Nausea, cramps and breast or menstrual changes.
When should I get medical help while using Spironolactone?
Weakness, palpitations, fainting or severe rash needs assessment.
Can Spironolactone interact with other medicines?
Potassium supplements, ACE inhibitors/ARBs, NSAIDs and lithium require review.
What should I know about Spironolactone during pregnancy or breastfeeding?
The Canadian reference restricts pregnancy and breastfeeding; discuss alternatives.
Sources and product information
Sources checked 2026-09-08. Safety sections are highlights; consult the full product information for complete warnings and instructions.
Check the Canadian Drug Product Database by product name or DIN for current product information.
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