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Care365 medication guide
Oxymetazoline nasal spray
Temporarily relieves a blocked nose.
Drug information
Uses, directions and safety information for Oxymetazoline nasal spray.
What it is used for
Temporarily relieves a blocked nose.
How to use it
Use only the age-appropriate product and labelled short course. Longer use can cause rebound congestion.
Before use
Review high blood pressure, heart disease, thyroid disease, diabetes and urinary problems.
Possible side effects
Nasal burning, dryness or sneezing.
When to get medical help
Seek care for marked palpitations, severe headache or accidental ingestion, especially by a child.
Medicines and interactions
Do not combine with an MAOI or use within its required washout period. Review other decongestants.
Pregnancy and breastfeeding
Ask before use in pregnancy or breastfeeding.
Missed doses, storage and accidental exposure
Follow your own product’s missed-dose instructions. If you are unsure, ask a pharmacist before taking an extra dose. Contraceptives, injections and modified-release medicines may need a specific plan.
Keep the original packaging and follow its storage, expiry and disposal instructions. Keep medicines away from children and pets. Ask about refrigeration, after-opening limits and safe sharps disposal when relevant.
For suspected overdose or accidental swallowing, contact poison control or urgent medical care promptly. Call emergency services for breathing difficulty, collapse or a seizure.
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Plan your follow-up
Follow the advice you receive about treatment, monitoring and next steps.
Related condition guides
Learn about concerns where this medication may be discussed. Treatment depends on your individual assessment.
Prescription renewal and medication review
For a review of Oxymetazoline nasal spray, have your current dose, reason for treatment, remaining supply, benefits, side effects and pharmacy details ready. Ask your pharmacist or prescriber whether a renewal assessment is available and appropriate. A prescription or renewal is not guaranteed.
Questions about Oxymetazoline nasal spray
What is Oxymetazoline nasal spray used for?
Temporarily relieves a blocked nose.
How should I use Oxymetazoline nasal spray?
Use only the age-appropriate product and labelled short course. Longer use can cause rebound congestion.
What side effects can Oxymetazoline nasal spray cause?
Nasal burning, dryness or sneezing.
When should I get medical help while using Oxymetazoline nasal spray?
Seek care for marked palpitations, severe headache or accidental ingestion, especially by a child.
Can Oxymetazoline nasal spray interact with other medicines?
Do not combine with an MAOI or use within its required washout period. Review other decongestants.
What should I know about Oxymetazoline nasal spray during pregnancy or breastfeeding?
Ask before use in pregnancy or breastfeeding.
Sources and product information
Sources checked 2026-09-08. Safety sections are highlights; consult the full product information for complete warnings and instructions.
Check the Canadian Drug Product Database by product name or DIN for current product information.
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