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Drug information
Uses, directions and safety information for Adapalene.
What it is used for
A retinoid treatment for acne.
How to use it
Apply a thin layer once nightly to clean, dry acne-prone skin. More does not work faster; improvement takes weeks.
Before use
Avoid eczema, broken or sunburned skin and ingredient allergy. Use sun protection; avoid waxing treated skin.
Possible side effects
Dryness, peeling, redness and stinging.
When to get medical help
Stop and seek help for severe burning, blistering or allergic swelling.
Medicines and interactions
Other retinoids, exfoliants and drying acne products can increase irritation.
Pregnancy and breastfeeding
Do not use during pregnancy or while planning pregnancy. Discuss breastfeeding use and avoid infant contact.
Missed doses, storage and accidental exposure
Follow your own product’s missed-dose instructions. If you are unsure, ask a pharmacist before taking an extra dose. Contraceptives, injections and modified-release medicines may need a specific plan.
Keep the original packaging and follow its storage, expiry and disposal instructions. Keep medicines away from children and pets. Ask about refrigeration, after-opening limits and safe sharps disposal when relevant.
For suspected overdose or accidental swallowing, contact poison control or urgent medical care promptly. Call emergency services for breathing difficulty, collapse or a seizure.
Care that starts with a conversation
How Care365 can help
Explore care for your symptoms and prepare for a conversation about treatment. Your healthcare professional will consider your history, current medicines and whether an assessment or referral is appropriate.
Your next steps
Know what to prepare and what to discuss.
Share your history
Prepare your symptoms, allergies, medication list and treatment questions.
Discuss your options
A healthcare professional assesses which care or referral is appropriate.
Plan your follow-up
Follow the advice you receive about treatment, monitoring and next steps.
Related condition guides
Learn about concerns where this medication may be discussed. Treatment depends on your individual assessment.
Prescription renewal and medication review
For a review of Adapalene, have your current dose, reason for treatment, remaining supply, benefits, side effects and pharmacy details ready. Ask your pharmacist or prescriber whether a renewal assessment is available and appropriate. A prescription or renewal is not guaranteed.
Questions about Adapalene
What is Adapalene used for?
A retinoid treatment for acne.
How should I use Adapalene?
Apply a thin layer once nightly to clean, dry acne-prone skin. More does not work faster; improvement takes weeks.
What side effects can Adapalene cause?
Dryness, peeling, redness and stinging.
When should I get medical help while using Adapalene?
Stop and seek help for severe burning, blistering or allergic swelling.
Can Adapalene interact with other medicines?
Other retinoids, exfoliants and drying acne products can increase irritation.
What should I know about Adapalene during pregnancy or breastfeeding?
Do not use during pregnancy or while planning pregnancy. Discuss breastfeeding use and avoid infant contact.
Sources and product information
Sources checked 2026-09-08. Safety sections are highlights; consult the full product information for complete warnings and instructions.
Check the Canadian Drug Product Database by product name or DIN for current product information.
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